Nowadays, more and more drugs commonly use cold aluminum as packaging material, mainly used to protect drugs from external environmental influences and extend their shelf life. How should we choose the appropriate thickness for medicinal cold aluminum as a packaging material?

1. Key considerations

1) Drug characteristics:

·Stability: Drugs sensitive to light, moisture, and oxygen require cold aluminum with higher barrier properties, i.e. thicker aluminum foil.

·Dosage form: Different dosage forms such as tablets, capsules, powders, liquids, etc. have different requirements for packaging materials.

2) Bubble depth:

·Shallow bubble cover: Suitable for thinner cold aluminum (such as 130-140 microns), it can provide sufficient protection and has a lower cost.

·Medium depth blister: Typically, medium thickness cold aluminum (such as 150-160 microns) is chosen to balance protective performance and economy.

·Deep bubble cover: requires thicker cold aluminum (such as 160 microns or above) to prevent cracking and deformation.

3) Storage and transportation conditions:

·Environmental conditions: Drugs stored and transported under high temperature, high humidity, or harsh conditions require packaging materials with higher barrier properties.

·Transportation distance and method: Drug packaging for long-distance transportation or frequent handling requires stronger materials.

4) Regulations and standards:

·The drug packaging regulations of various countries may have specific requirements for the thickness of cold aluminum, which need to comply with relevant laws and standards.

5) Cost effectiveness:

·Cost: Thicker cold aluminum is usually more expensive, so it is necessary to consider the cost comprehensively while meeting the protection needs.

·Cost effectiveness: Choose a cold aluminum thickness that provides both sufficient protection and cost-effectiveness.